Search on: PROTO-ONCOGENE PROTEINS C-FES 
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Descriptor English:   Proto-Oncogene Proteins c-fes 
Descriptor Spanish:   Proteínas Proto-Oncogénicas c-fes 
Descriptor Portuguese:   Proteínas Proto-Oncogênicas c-fes 
Synonyms English:   c-fes Proteins
fes Proto-Oncogene Proteins
fps Proto-Oncogene Protein  
Tree Number:   D08.811.913.696.620.682.725.300
D12.776.624.664.700.177
Definition English:   Proto-oncogene proteins fes are protein-tyrosine kinases with a central SH2 DOMAIN. It has been implicated in SIGNAL TRANSDUCTION PATHWAYS for CELL DIFFERENTIATION of a variety of cell types including MYELOID PROGENITOR CELLS. Fes proto-oncogene proteins also bind TUBULIN and promote MICROTUBULE assembly. 
History Note English:   2006(1986) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   50731 
Unique Identifier:   D051578 

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